Strength: 100,000 IU/mL 5 mL Vial

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Vitamin D is a fat-soluble vitamin and has two primary forms: cholecalciferol (vitamin D3) and ergocalciferol (vitamin D2). Cholecalciferol has a 10-fold increased potency as compared to ergocalciferol. Furthermore, it induces a quicker response in the production of serum calcidiol that sustains longer at higher concentrations. Various foods are fortified with vitamin D, including milk and cereal. Other dietary sources include fish liver oils, fatty fish, and eggs from hens that have been supplemented with vitamin D.

Cholecalciferol is synthesized by the skin after exposure to sunlight. In healthy individuals, 7-dehydrocholesterol in the skin is converted to cholecalciferol. Brief exposure of approximately 20% of body surface area to sunlight is equivalent to ingesting 200 IU of cholecalciferol. Thus, cutaneous production is highly efficient. However, many individuals lack the ability to efficiently produce adequate stores of cholecalciferol. Therefore, cholecalciferol supplementation is essential.

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